Piper Review
An in-depth look at Piper — a telehealth platform offering compounded semaglutide from $135/month and tirzepatide from $199/month with overnight delivery and availability in all 50 states.
Piper
Overnight DeliveryPiper is a telehealth platform offering compounded GLP-1 medications with a focus on transparent pricing, fast delivery, and data-driven results. Their semaglutide starts at $135/month and tirzepatide at $199/month — both with flat-rate pricing that stays the same regardless of dose level.
One of Piper's standout features is overnight delivery included at no extra cost — significantly faster than the 3–5 business day shipping most competitors offer. They also provide same-day doctor visits, a 24/7 patient portal, and HSA/FSA eligibility.
Available in all 50 US states, Piper takes a data-driven approach that emphasizes measurable improvements in health markers alongside weight loss, including appetite control, blood sugar, and blood pressure improvements.
Visit Piper$135/mo
Semaglutide Starting Price
$199/mo
Tirzepatide Starting Price
Next Day
Overnight Delivery
50
US States Available
Available Medications
Flat-rate pricing at every dose — no surprise price jumps. HSA/FSA eligible.
Compounded Semaglutide
The same active ingredient found in Ozempic and Wegovy. Weekly subcutaneous injection with an average weight loss of ~16% of body weight in clinical trials.
$135/mo
All doses, same flat rate
- ✓Weekly subcutaneous injection
- ✓~16% average body weight reduction
- ✓Clinician oversight & supplies included
- ✓Free overnight delivery
Compounded Tirzepatide
The same active ingredient found in Mounjaro and Zepbound. Dual GIP/GLP-1 receptor agonist with an average weight loss of ~22% in clinical trials.
$199/mo
Most Popular
- ✓Weekly subcutaneous injection
- ✓~22% average body weight reduction
- ✓Dual GIP/GLP-1 mechanism
- ✓Free overnight delivery
What's Included
Every Piper plan includes clinician oversight, overnight delivery, and 24/7 portal access.
Medication
Compounded semaglutide or tirzepatide prescribed by a licensed clinician
Injection Supplies
All syringes, alcohol swabs, and supplies needed for self-administration
Same-Day Doctor Visits
Licensed clinicians available for same-day consultations when needed
Overnight Delivery
Next-day shipping on all approved treatments at no extra cost
24/7 Patient Portal
Access your treatment plan, track progress, and message your care team anytime
Ongoing Follow-Up
Continued clinical support with dose adjustments and regular check-ins
Pros & Cons
Our honest assessment of Piper after evaluating their platform, pricing, and patient experience.
Pros
- ✓Competitive pricing — semaglutide from $135/month, tirzepatide from $199/month
- ✓Flat-rate pricing — same cost for every dose level with no hidden fees
- ✓Overnight delivery included at no extra cost
- ✓Available in all 50 US states
- ✓Same-day doctor visits when needed
- ✓HSA/FSA eligible — use pre-tax health savings
- ✓24/7 patient portal for tracking and messaging
- ✓Data-driven approach with measurable health marker improvements
Cons
- ✕Compounded medications are not FDA-approved brand-name drugs
- ✕Not covered by insurance since medications are compounded
- ✕Newer platform — less track record compared to established competitors
- ✕No oral or non-injection options available
How It Works
Getting started with Piper takes just a few minutes. Here's the full process.
Online Assessment
Complete a short health questionnaire covering your goals, lifestyle, and medical background — takes just a few minutes.
Doctor Review
A licensed clinician reviews your answers and creates a tailored treatment plan that's safe and effective for your needs.
Fast Delivery
Once approved, your medication ships with overnight delivery directly to your door — no extra delivery cost.
Ongoing Support
Your care team monitors your progress, adjusts dosing, and provides clinical guidance through your 24/7 patient portal.
Who Is Piper Best For?
Great Fit
- ✓Patients who want fast medication delivery — overnight shipping included
- ✓Anyone looking for competitive, flat-rate GLP-1 pricing
- ✓People who want to use HSA/FSA pre-tax dollars
- ✓Patients who value 24/7 portal access and same-day doctor availability
May Not Be Ideal For
- —Patients who require FDA-approved brand-name medications
- —Those who prefer oral medications over injections
- —Patients looking for insurance-covered weight loss treatment
Frequently Asked Questions
How much does Piper cost?
Piper offers compounded semaglutide at $135/month and compounded tirzepatide at $199/month. Both use flat-rate pricing — the cost stays the same regardless of your dose level. There are no hidden fees, and overnight shipping is included.
How fast will I receive my medication?
Piper offers overnight delivery on all approved treatments at no extra cost. Once your clinician approves your treatment plan, medication ships the next business day and arrives the following day.
What kind of weight loss can I expect?
Based on clinical data, patients on semaglutide can expect an average weight loss of about 16% of body weight, while tirzepatide patients can expect about 22%. Individual results vary based on adherence, diet, exercise, and other factors.
Is Piper available in my state?
Yes. Piper offers telehealth services in all 50 US states, so you can access treatment from anywhere in the country.
Can I use my HSA or FSA?
Yes. Piper is HSA/FSA eligible, meaning you can use pre-tax dollars from your health savings or flexible spending account to pay for treatment.
What is 'food noise' reduction?
GLP-1 medications like semaglutide and tirzepatide work by mimicking hormones that regulate appetite. Many patients report a significant reduction in 'food noise' — the constant thoughts about food and cravings that can make weight management difficult. This effect typically begins within the first few weeks of treatment.
Ready to Get Started?
Start your weight loss journey with Piper — compounded GLP-1 medications with flat-rate pricing, overnight delivery, and availability in all 50 states.
Visit PiperCompare Other GLP-1 Providers
See how other telehealth providers stack up.
CoreAge Rx
#1 RecommendedFlat-rate pricing for compounded semaglutide and tirzepatide with NABP-verified pharmacies
Read Review →BeyondMD
Top RatedBoard-certified physician-led care with comprehensive medical oversight
Read Review →Henry Meds
Top RatedWell-established telehealth platform with fast physician reviews and competitive pricing
Read Review →Alan Meds
Top RatedAffordable compounded GLP-1s with board-certified physicians and straightforward pricing
Read Review →Mochi Health
Obesity Medicine SpecialistsBoard-certified obesity medicine specialists with both brand-name and compounded GLP-1 options
Read Review →PlushCare
Insurance AcceptedMajor telehealth platform with brand-name FDA-approved GLP-1s, insurance support, and 1M+ members treated
Read Review →Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. Compounded medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. Individual results may vary. Always consult a qualified healthcare provider before starting any new medication.
Affiliate Disclosure: This site may receive compensation from affiliate partners, including Piper. This does not influence our editorial content or review ratings. We only recommend providers we believe offer genuine value to patients.