R&R CBD Review

There is exactly one FDA-approved CBD medicine: Epidiolex, for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. Everything else sold as CBD — including everything R&R sells — has not been evaluated by the FDA for the purposes people buy it for. The FDA has stated that it is not apparent how CBD products could meet the safety standard required of a dietary supplement or food additive, and has concluded the existing frameworks are not appropriate for CBD.

The practical safety issue is interactions. CBD is metabolised by CYP450 enzymes, mainly CYP3A4 and CYP2C19, and can shift the blood levels of other drugs using those pathways — and vice versa. Liver enzyme elevation has been observed at pharmaceutical CBD doses. None of this makes CBD unusually dangerous, but it does mean “it's natural, so it's fine alongside my prescriptions” is wrong. Ask a pharmacist; they will check your full medication list for free in a few minutes.

How much does R&R CBD cost?

Checked on 29 July 2026, published prices are: 30mg multifunctional CBD gummies (30 count) $58, 60mg $84, 90mg $103; sleep, pain and de-stress gummies $68 each; 1000mg tincture $58 and 2500mg tincture $88; pain creams $58 (1000mg), $88 (2500mg) and $133 (5000mg); and THC gummies (20 count, 5mg THC + 10mg CBD) $48. Subscribe & Save cuts 20% off, bundles save 10% on two items or 15% on three or more, US shipping is free over $60 and subscriptions always ship free. There is a 60-day money-back guarantee.

Is CBD an approved supplement?

No, and this applies to the whole category rather than to R&R specifically. The only FDA-approved CBD medicine is Epidiolex, prescribed for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. For everything else, FDA has stated that it is not apparent how CBD products could meet the safety standard required to be lawfully marketed as a dietary supplement or food additive, and it has concluded that the existing regulatory frameworks are not appropriate for CBD — it is working with Congress on a new pathway. In practice CBD is sold in a regulatory grey area. That does not make it dangerous, but it does mean no CBD product has been evaluated by FDA for the uses people buy it for.

Will CBD interact with my medications?

It can, and this is the safety point most worth your attention. CBD is metabolised by cytochrome P450 enzymes — principally CYP3A4 and CYP2C19 — and can affect the levels of other drugs processed by the same pathways, as well as being affected by them. Data from the approved CBD drug show real potential for clinically meaningful interactions. Liver enzyme elevation has also been observed at pharmaceutical doses. If you take prescription medication of any kind — and particularly blood thinners, anticonvulsants or anything with a narrow therapeutic window — check with a pharmacist or your prescriber before starting CBD. A pharmacist will do this for free.

Does CBD help with weight loss?

No. There is no credible evidence that CBD causes weight loss, and it is not a GLP-1 medication, an appetite suppressant, or a substitute for one. We include CBD brands on this site because readers ask about sleep and discomfort during weight-loss treatment, not because CBD does anything to body weight. If a product anywhere claims CBD will help you lose weight, that claim is not supported.

Will full-spectrum CBD show up on a drug test?

It can. Full-spectrum products legally contain up to 0.3% delta-9 THC, and repeated use can produce enough THC metabolite to trigger a positive urine screen. If you are subject to any workplace, athletic or legal drug testing, choose R&R's THC-free broad-spectrum versions, which are available in gummies, tinctures and creams. Also note R&R sells actual THC gummies (5mg THC each) — those will certainly show up and are a different product category entirely.

Is R&R CBD a legitimate brand?

Within a category full of unverifiable claims, R&R's credentials stand out because they are externally auditable. USDA organic certification is a real government-recognised programme with inspections, not marketing language. US Hemp Authority certification adds a manufacturing and labelling standard. And the published lab reports go beyond a single CBD number to include terpene content. Independent CBD reviewers have consistently found its potency labelling accurate — which matters, because studies of the wider market have repeatedly found a large share of CBD products mislabelled. Combined with a 60-day money-back guarantee, this is about as much verification as the category currently offers.

Who should not take CBD?

Avoid it if you are pregnant or breastfeeding, and speak to a clinician first if you have liver disease, take medication with a narrow therapeutic window, or are under 18. CBD is not appropriate as a replacement for prescribed treatment for any condition. Common side effects include drowsiness, diarrhoea, dry mouth, reduced appetite and changes in liver enzymes. This is informational only, not medical advice.