GLP-1 Guide

Sesame Review

An in-depth look at Sesame — a telehealth platform offering 14 FDA-approved weight loss medications, provider choice, insurance navigation, and included lab testing for $99/month.

Sesame

14 Medication Options
4.6 / 5

Sesame stands out with the widest medication selection of any telehealth weight loss platform we've reviewed — 14 different prescription options including brand-name Wegovy, Zepbound, Ozempic, and more. Unlike most competitors, Sesame focuses exclusively on FDA-approved medications rather than compounded alternatives.

The program costs $99 every 28 days and includes video consultations, lab testing, unlimited messaging, and clinical oversight. Medication is billed separately — but with Sesame's insurance navigation, brand-name GLP-1s can cost as little as $25/month with coverage. Without insurance, Wegovy starts at $349/month through their Costco Pharmacy partnership.

A unique feature is provider choice — you can browse providers, read reviews, and select who you want to work with for continuity of care. Same-day consultations are also available.

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$99

Program Fee / 28 Days

14

Medication Options

$25

GLP-1 w/ Insurance

Included

Labs & Video Visits

Available Medications

14 FDA-approved prescription options. Insurance concierge included to help reduce medication costs.

Wegovy (Semaglutide)

FDA-approved brand-name semaglutide injection for weight management. Insurance navigation included to help lower costs.

$349 /mo (Costco)

As low as $25/month with insurance

  • FDA-approved brand-name medication
  • Insurance navigation included
  • Oral pill option available
  • Labs and video visits included
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Zepbound (Tirzepatide)

FDA-approved brand-name tirzepatide injection for weight management. Vial pricing available through Sesame partnership.

$349 /mo (vials)

$349–$499/month depending on dose

  • FDA-approved brand-name medication
  • Dual GIP/GLP-1 mechanism
  • Insurance navigation included
  • Labs and video visits included
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What's Included

The $99/28-day program fee includes provider access, labs, messaging, and clinical oversight. Medication billed separately.

Video Consultations

Unlimited video visits with your chosen provider, including same-day consultation availability

Provider Choice

Browse and select your preferred provider based on experience, specialty, and patient reviews

Lab Testing

Blood work through Quest Diagnostics included in most states

Unlimited Messaging

Ongoing communication with your chosen provider between visits

Insurance Navigation

Help with prior authorization to reduce medication costs — potentially $25/month with coverage

14 Medication Options

Access to the widest selection of weight loss medications including brand-name GLP-1s

Pros & Cons

Our honest assessment of Sesame after evaluating their platform, pricing, and customer experience.

Pros

  • Brand-name FDA-approved medications available (Wegovy, Zepbound, Ozempic)
  • Widest medication selection — 14 different prescription options
  • Choose your own provider based on reviews and ratings
  • Very affordable with insurance — as low as $25/month for brand-name GLP-1s
  • Same-day consultations available
  • Transparent $99/month program fee with no hidden costs
  • Lab testing included in most states
  • Unlimited messaging and video visits with your provider

Cons

  • No compounded medication options — brand-name only, which can be expensive without insurance
  • 28-day billing cycle instead of calendar monthly can complicate budgeting
  • Lab testing not available in 9 states (AZ, HI, ND, NJ, NY, OK, RI, SD, WY)
  • Limited lifestyle coaching — no meal planning or nutrition support
  • Some reports of slow customer service and cancellation difficulties
  • Variable provider quality depending on who you select

How It Works

Getting started with Sesame is straightforward. Here's the process.

1

Online Assessment

Complete an initial health questionnaire covering your medical history, current medications, and weight loss goals.

2

Choose Your Provider

Browse available providers, read reviews, and select the one that best fits your needs and preferences.

3

Video Consultation

Meet with your chosen provider via video — same-day appointments available. Get a personalized treatment plan.

4

Ongoing Care

Receive your prescription, complete lab work, and stay connected with unlimited messaging and follow-up visits.

Who Is Sesame Best For?

Great Fit

  • Insured patients who want help maximizing GLP-1 coverage
  • Anyone who wants to choose their own provider
  • Patients who prefer FDA-approved brand-name medications
  • Those who want the widest selection of medication options

May Not Be Ideal For

  • Uninsured patients looking for affordable compounded options
  • Those who want intensive nutrition coaching or meal planning
  • Patients in states without lab coverage (AZ, HI, ND, NJ, NY, OK, RI, SD, WY)

Frequently Asked Questions

How much does Sesame cost?

The Sesame weight loss program costs $99 every 28 days, which includes video consultations, lab work (in most states), unlimited messaging, and clinical oversight. Medication is billed separately. With insurance, brand-name GLP-1s can be as low as $25/month. Without insurance, Wegovy starts at $349/month through Costco Pharmacy, and Zepbound vials start at $299–$499/month.

Does Sesame offer compounded medications?

No. Sesame focuses exclusively on FDA-approved brand-name medications including Wegovy, Zepbound, Ozempic, and others. They do not offer compounded semaglutide or tirzepatide. This means medications may be more expensive without insurance but are fully FDA-approved.

Can I choose my own provider?

Yes. Unlike most telehealth weight loss platforms that randomly assign providers, Sesame lets you browse available providers, read patient reviews, and choose who you want to work with. You can continue seeing the same provider for continuity of care.

Are labs included?

Lab testing through Quest Diagnostics is included in most states. However, labs are not currently available in Arizona, Hawaii, North Dakota, New Jersey, New York, Oklahoma, Rhode Island, South Dakota, and Wyoming.

Does Sesame work with insurance?

Yes. Sesame helps navigate insurance coverage through prior authorization. If your insurance covers GLP-1 medications, you may pay as little as $25/month for brand-name Wegovy or Zepbound. The $99/month program fee itself is not covered by insurance.

How many medication options are available?

Sesame offers 14 different prescription weight loss medications — the widest selection we've seen among telehealth providers. Options include Wegovy, Zepbound, Ozempic, Rybelsus, metformin, and others. Your provider will help determine the best option based on your health profile.

Ready to Get Started?

Start your weight loss journey with Sesame — 14 FDA-approved medication options, provider choice, insurance navigation, and included labs for $99/month.

Visit Sesame

Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. GLP-1 medications require a prescription. Individual results may vary. Always consult a qualified healthcare provider before starting any new medication.

Affiliate Disclosure: This site may receive compensation from affiliate partners, including Sesame. This does not influence our editorial content or review ratings. We only recommend providers we believe offer genuine value to patients.