Please note: This review reflects information we gathered on the date it was researched and may now be out of date. Providers frequently change their pricing, plans, medications, and policies. Any ratings, reviews, and customer feedback are gathered from publicly available online sources and may have since changed or no longer be accurate. Always do your own research and confirm the latest details directly with the provider before making any decision.
Cannanine Review
No xylitol, no THC, dosing by body weight — the right choices for a dog. Then we compared the dropper chart with the dose the trials actually used.
Cannanine
Careful Formula, Light DoseThe safety checks pass: we searched 79,000 characters of product copy for xylitol — which causes hypoglycaemia and liver failure in dogs — plus grapes, raisins, garlic, onion, macadamia and chocolate. Zero mentions. The oils state “Our product contains no THC”, which matters because dogs are far more THC-sensitive than people. Certificate linked, human-grade ingredients, and dosing charted by body weight.
But do the arithmetic: the 250mg oil is 8.33mg/ml, so the standard dose for a 6-11 lb dog is about 2mg — roughly 0.42mg/kg/day. The Cornell osteoarthritis trial used 2mg/kg twice daily — 4mg/kg/day. That is nearly ten times more, and even the “stronger dose” is about five times short. So you cannot reason from the trials to this bottle.
Checked 8 August 2026: oils $29.99-$69.99, PCR oil $44.99, bacon CBD chews $24.99-$39.99, mushroom chews $34.99. The free trial is an autoship and says so — the renewal price is in the product title. Refunds cover unopened product within 90 days. Donations are quantified: 7 shelter meals per oil bottle.
Affiliate disclosure: GLP1Drugs.org earns 25% here — among the highest rates in our queue, about $7.50 on a $29.99 bottle. Our central finding is still that the label dose is a fraction of the researched dose. This is also an off-category offer: nothing here relates to GLP-1 treatment. Verified 8 August 2026.
Visit CannanineOur Top Recommended Provider: CoreAge Rx
After reviewing dozens of GLP-1 telehealth providers, CoreAge Rx is the one we recommend most. CoreAge Rx is one of our partners — read on for why we recommend them:
Flat-Rate Pricing
Same cost at every dose level — no price jumps as you titrate up.
Verified Pharmacies
US-licensed physicians and NABP-verified 503A compounding pharmacies you can trust.
Everything Included
Medication, supplies, free shipping, and ongoing clinical support — no hidden fees.
Active Community of Members
Ask questions, share progress, and get answers from other patients on the same journey — alongside ongoing clinical support from your care team.
0
Mentions Of Xylitol
0.42
mg/kg/day On The Label
4.0
mg/kg/day In The Trial
25%
Commission This Pays Us
What We Verified
Catalogue and product copy pulled from cannanine.com's store API and searched for canine toxins; dosing arithmetic is ours, on the brand's own figures. 8 August 2026.
We Searched For Xylitol And Found None
Xylitol causes hypoglycaemia and liver failure in dogs and turns up in human-formulated products. We searched 79,000 characters of Cannanine's product copy for it, plus grapes, raisins, garlic, onion, macadamia and chocolate. Zero mentions of any
And It Is Explicitly THC-Free
"Our product contains no THC." Dogs are markedly more sensitive to THC than humans, and broad-spectrum rather than full-spectrum is the correct choice for a pet product. Note the affiliate brief's URLs still say "full-spectrum" — the products do not
Dosing Is By Body Weight, Which Most Brands Skip
The oils carry a weight-banded chart — 1/8 dropper for 0-5 lb, 1/4 for 6-11 lb, with a standard and a stronger dose — plus strength guidance by dog size. That is proper species-appropriate instruction
But It Is About A Tenth Of The Studied Dose
At 250mg in 30ml the oil is 8.33mg/ml, so the standard dose for a 6-11 lb dog is roughly 2mg — about 0.42mg/kg/day. The Cornell osteoarthritis trial used 2mg/kg twice daily, or 4mg/kg/day. Nearly ten times more
The Free Trial Is A Subscription, And Says So
"This free trial includes a subscription that autoships… then every 2-8 weeks thereafter at 15% off MSRP ($39.99)." The renewal price is even in the product title. That is far better disclosure than most negative-option trials
The "Only Hemp Oil Endorsed By iHeartDogs" Is Self-Endorsement
Cannanine sits in the same product family as iHeartDogs, whose branded probiotics, multivitamins and dental chews share this checkout. An endorsement from a sister brand is marketing, not third-party validation
The Dropper Chart Against The Research
Our arithmetic on Cannanine's published concentration and dosing chart, compared with the Cornell protocol. Discuss dosing with your vet, not with us.
| Regimen | Amount | Per kg Per Day | Versus The Trial |
|---|---|---|---|
| Cornell protocol | 2mg/kg twice daily | 4.0 mg/kg | The dose with published trial evidence |
| Label, stronger dose | 0.5ml = 4.2mg (11 lb dog) | ~0.84 mg/kg | About 5x lower |
| Label, standard dose | 0.25ml = 2.1mg (11 lb dog) | ~0.42 mg/kg | About 10x lower |
| Bottle concentration | 250mg in 30ml | 8.33 mg/ml | The figure the maths above rests on |
Nothing here relates to weight-loss medication — this is a pet product and we have reviewed it as one. If you want the human side of this site, our side-effects guide and provider rankings are the useful pages.
Pros & Cons
Pros
- ✓No xylitol anywhere in the product copy we searched — the single most important safety check for anything you give a dog
- ✓No grapes, raisins, garlic, onion, macadamia or chocolate mentioned either
- ✓Explicitly THC-free: "Our product contains no THC", which matters because dogs are far more sensitive to THC than people
- ✓Weight-banded dosing charts with both a standard and a stronger dose, plus bottle-strength guidance by dog weight
- ✓A certificate of analysis is linked directly from the product page rather than buried
- ✓Stated to be tested and free of heavy metals, harmful bacteria, yeast, mould and other toxins
- ✓Made from human-grade ingredients and manufactured in the USA from organically grown Colorado hemp
- ✓Claims stay in structure-function language — "supports joint mobility", "promotes a healthy inflammation response" — rather than claiming to treat arthritis
- ✓The free-trial subscription is disclosed unusually clearly, with the renewal price stated in the product title itself
- ✓Subscriptions can be cancelled at any time and the delivery interval is customer-selected between 2 and 8 weeks
- ✓A 90-day refund window on unopened product, which is longer than most
- ✓Charitable donations are quantified per product — 7 shelter meals per oil bottle, 3 per balm — rather than a vague pledge to give back
- ✓Separate $2 "Donate A Dose" items let you fund CBD for hospice and shelter dogs without buying for your own
- ✓The veterinary evidence base for CBD in canine osteoarthritis is genuinely better than the human evidence behind most CBD marketing
Cons
- ✕The label dose is roughly 0.4mg/kg/day against 4mg/kg/day in the published Cornell trial — about ten times lower
- ✕Even the "stronger dose" lands near 0.84mg/kg/day, still nearly five times below the studied regimen
- ✕Those trials tested specific formulations at specific doses, not this product, so positive findings do not transfer automatically
- ✕Elevated liver enzymes have been reported in canine CBD research, which means a vet should be involved and monitoring considered
- ✕Anchor pricing throughout: "One bottle: $29.99 ($49.99 value)" and "$44.99 ($65 value)" against prices nobody appears to pay
- ✕The 90-day refund covers unopened product only, so a jar you have opened and your dog dislikes is not returnable
- ✕"The only hemp oil endorsed by iHeartDogs.com" is an endorsement from a sister brand in the same product family
- ✕A patented "Nano-Sized Microemulsion" is claimed to be 4x smaller than liposomal emulsion for bioavailability, with no data we could check
- ✕Heavy promotional scaffolding — BOGO offers, free sock monkeys, heartbeat pillows, tree toppers, seasonal deals and free trials
- ✕CBD is not FDA-approved for animals and there is no officially established dose for dogs or cats
- ✕Nothing here relates to GLP-1 treatment; this is an off-category offer and we have reviewed it as a pet product
- ✕Commission is 25%, among the highest rates in our queue, which is worth knowing when reading any recommendation
Our Verdict
3.8 / 5 — one of the more carefully made products in an unregulated category, dosed well below the research.
Pet supplements are a category with almost no premarket oversight, so the first job is checking whether anything in the bottle can hurt the animal. Cannanine passes those tests. We searched roughly 79,000 characters of its product copy for xylitol — a sweetener that causes rapid hypoglycaemia and can cause liver failure in dogs, and which appears in many products formulated for humans — along with grapes, raisins, garlic, onion, macadamia and chocolate. Not one mention of any of them. The oils state plainly that the product contains no THC, and every item we catalogued is broad spectrum rather than full spectrum, which is the correct choice given that dogs are markedly more sensitive to THC than people and cannabis toxicosis is a routine veterinary emergency. Beyond that, a certificate of analysis is linked from the product page, the oil is stated to be free of heavy metals, bacteria, yeast and mould, ingredients are described as human-grade from organically grown Colorado hemp, and — unusually — dosing is charted by body weight with both a standard and a stronger option. Claims stay in structure-function language rather than promising to treat arthritis. After a month of reviewing human CBD brands that name diseases on the label, this is a more careful operation than most.
Something else worth saying, because it surprised us: the veterinary evidence for CBD in canine osteoarthritis is genuinely better than the human evidence behind most CBD marketing. There is a double-blind, placebo-controlled trial from Cornell's College of Veterinary Medicine, published in Frontiers in Veterinary Science in 2018, using validated pain instruments in dogs with osteoarthritis, with further trials since. Then we did the arithmetic, and that is where the review turns. That protocol used 2mg of CBD per kilogram twice daily — 4mg/kg/day. Cannanine's 250mg oil is a 30ml bottle, so 8.33mg/ml. Its published chart gives a 6-to-11-pound dog a quarter-dropper, 0.25ml, which is 2.08mg — about 0.42mg/kg/day for an 11-pound dog. That is nearly ten times less than the studied dose, and the 'stronger dose' option is still roughly five times short. Dosing in this field is unsettled and we are comparing a label against one protocol, so this is not proof the product does nothing. It does mean the trials cannot be used to justify the bottle, and that if mobility in an older dog is your reason for buying, the dose is a question for your vet.
Credit on the commercial terms, which we expected to be worse. The free trial is a negative-option autoship — and it says so, explicitly, stating that the trial includes a subscription, naming the recurring price, letting you pick a 2-to-8-week interval and confirming you can cancel any time. One product title contains the renewal price outright. That is better disclosure than several brands we reviewed this month that charge far more. Refunds run 90 days on unopened product, which is generous in window and restrictive in condition — an opened jar your dog refuses is not returnable. The donations are quantified per unit rather than gestural: seven shelter meals per oil bottle, three per balm, plus standalone $2 items funding CBD for hospice dogs. What we would discount: the anchor pricing throughout, where $29.99 is presented against a $49.99 'value'; the 'patented Nano-Sized Microemulsion' claimed as 4x smaller than liposomal, since a patent covers novelty rather than efficacy and we found no data; and 'the only hemp oil endorsed by iHeartDogs.com', which is a sister brand in the same catalogue endorsing itself.
So: buy it as a general wellness product from a brand that has made the right formulation choices, and use the free trial if you like — but diarise the renewal. Do not buy it instead of veterinary care for a dog in pain. The research used ten times this dose, elevated liver enzymes have been reported in canine CBD studies, and there are licensed veterinary medicines for canine osteoarthritis with far stronger evidence than any CBD product. Ask your vet first. And to be straightforward about two things: this is an off-category offer with no relationship to GLP-1 treatment, and it pays us 25% — among the highest rates in our queue, roughly $7.50 on a $29.99 bottle — which is precisely why the headline of this review is that the dose is a tenth of the studied one.
Visit CannanineFrequently Asked Questions
Is it safe to give a dog CBD from this brand?
On formulation, the checks that matter come back well — and we ran them specifically because pet products are where human-formulated ingredients cause real harm. The first is xylitol, a sweetener that causes rapid hypoglycaemia and can cause liver failure in dogs, and which appears in plenty of products made for people. We searched roughly 79,000 characters of Cannanine's product descriptions for xylitol, and for grapes, raisins, garlic, onion, macadamia and chocolate: zero mentions of any of them. The second is THC, and this matters more than most owners realise. Dogs are considerably more sensitive to THC than humans, and cannabis toxicosis in dogs — ataxia, incontinence, disorientation, low body temperature — is a common emergency presentation. Cannanine states plainly: "Our product contains no THC." Every product in the range we catalogued is described as broad spectrum, which is the THC-free designation and the right choice for an animal. One point of confusion to flag: the affiliate material we were given contains URLs reading "organic-full-spectrum-cbd-oil", while the products themselves are all named broad spectrum. We take those to be legacy web addresses rather than a different product, but for a dog it is a distinction worth being certain about, so read the actual bottle. And two caveats on our method: absence from marketing copy is not the same as reading a physical label, and we did not open a certificate ourselves.
Does CBD actually work for dogs?
This is the part that surprised us, and it deserves stating clearly: the veterinary evidence for CBD in canine osteoarthritis is better than the human evidence behind most of the CBD marketing we have reviewed this month. There is a double-blind, placebo-controlled trial from Cornell University's College of Veterinary Medicine — Gamble and colleagues, published in Frontiers in Veterinary Science in 2018 — which examined pharmacokinetics, safety and clinical efficacy in dogs with osteoarthritis, using validated instruments including the Canine Brief Pain Inventory and the Hudson Visual Analog Scale. Further trials have followed. That is a proper study design applied to a specific condition, which is more than can be said for the human claims about sleep, stress and skin we have spent this month picking apart. We should be straight about the limits of what we verified: we did not read the full paper and we are not certifying its effect sizes. And there is a safety signal in this literature worth knowing — increases in alkaline phosphatase, a liver enzyme, have been reported in canine CBD research, which is precisely why a vet should be involved rather than this being a purely retail decision. So: real evidence exists, for one condition, at particular doses. Which brings us to the problem with the bottle.
What is the problem with the dose?
It appears to be about a tenth of the dose the trials used, and this is the central finding of our review because it is arithmetic on the company's own numbers rather than an opinion. The Cornell protocol administered 2mg of CBD per kilogram of body weight, twice daily — so 4mg/kg per day. Now take Cannanine's 250mg oil, which is a 30ml bottle: that is 8.33mg of CBD per millilitre. The published dosing chart gives a 6-to-11-pound dog a standard dose of a quarter of a dropper, or 0.25ml. That is 2.08mg of CBD. An 11-pound dog is about 5kg, so the standard dose works out at roughly 0.42mg/kg per day — against 4mg/kg per day in the trial. Nearly ten times lower. Even the "stronger dose" option of double that lands near 0.84mg/kg per day, still almost five times below. We are comparing a label instruction with one published protocol, and dosing in this field is genuinely unsettled, so this is not proof the product does nothing. But it does mean you cannot reason from "trials show CBD helps arthritic dogs" to "therefore this bottle at this dose will help my arthritic dog" — the doses are not comparable. If mobility in an older dog is why you are buying, that is exactly the conversation to have with your vet, who can advise on an appropriate amount rather than leaving you to a dropper chart.
Is the free trial a trap?
It is a negative-option subscription, and it is disclosed better than almost any we have seen — which is worth saying because this pattern is usually where consumer harm lives. Here is the company's own wording: "Customers signing up will receive a free 60-count jar, and we'll send it for just the cost of shipping and tax. (Domestic orders only). This free trial includes a subscription that autoships Cannanine CBD Soft Chews 60-count jar in the time frame the customer selects (Anywhere from 2-8 weeks) after the initial free order is placed, then every 2-8 weeks (based on selected timeframe) thereafter at 15% off MSRP ($39.99) + shipping & tax. Cancel the subscription any time – it's really that simple!" Note what that does: it says explicitly that the trial includes a subscription, states the recurring price, lets you choose the interval, and says you can cancel any time. One of the product titles literally contains the renewal price — "renews at $33.99 – 15% Off Regular Price: $39.99" — which is more transparency than we found at several brands charging considerably more. The limitation is the refund condition: unopened product can be returned within 90 days, so if a jar arrives, you open it and your dog will not eat the chews, that jar is not coming back. Our advice is the same as for any autoship: diarise the renewal, cancel in the account rather than by email, and keep the confirmation.
How trustworthy are the quality claims?
Better documented than most, with two claims we would treat as marketing. On the good side: a certificate of analysis is linked directly from the product page rather than requiring a hunt, the oil is stated to be "tested and found to be free of heavy metals, harmful bacteria, yeast, mold, and other toxins", it is described as made from human-grade ingredients and manufactured in the USA from organically grown Colorado hemp, and there is weight-banded dosing guidance. For a pet supplement — a category with essentially no premarket regulation and a long history of label inaccuracy — that is a respectable disclosure package, and we did not find the disease claims that got several human CBD brands criticised elsewhere on this site. The claims we would discount: first, "features patented Nano-Sized Microemulsion for maximum bioavailability and absorbability (4x smaller particles compared to Liposomal emulsion)". A patent covers novelty, not efficacy, and a particle-size comparison is not a bioavailability outcome; we found no data to check that against. Second, "the only hemp oil endorsed by iHeartDogs.com" reads like third-party validation but iHeartDogs products — probiotics, multivitamins, dental chews — sit in the same catalogue and product family. That is a sister brand endorsing a sister brand, which is advertising. Neither is dishonest, but neither should move your decision.
What does it cost and is the charity element real?
Prices are moderate, the discount architecture is noisy, and the donation claims are refreshingly specific. Checked on 8 August 2026: the Ultra-Premium Broad Spectrum oil for dogs and cats is $29.99 for 250mg, with 500mg and 1,000mg versions listed variously at $29.99, $49.99 and $69.99 across SKUs; the Organic Broad Spectrum PCR oil is $44.99; bacon-flavoured CBD soft chews run $24.99 to $39.99 for 60 counts; CBD mushroom chews with turkey tail are $34.99; and multi-buy bundles reach $107.99. Alongside those sit non-CBD lines — Pupkin probiotics, a 24-in-1 multivitamin, dental powders, Honey Guard allergy products. What we would flag is the anchoring: "One bottle: $29.99 ($49.99 value)" and "$44.99 ($65 value)" present reference prices that nothing on the site suggests anyone actually pays, and the store is thick with BOGO offers, free sock monkeys, heartbeat pillows and seasonal gifts. On the charity side, the claims are quantified per product rather than gestural: an oil bottle "provides 7 healthy meals to shelter pets in need", the allergy balm donates 3 meals per purchase, and there are standalone $2 "Donate A Dose" items funding CBD for hospice and shelter dogs. Quantified per-unit donations are a better standard than "we give back", and we credit that — while noting we have not audited delivery of the meals.
Why is a dog product on a GLP-1 site?
Because it came through the same affiliate queue, and we would rather tell you that plainly than invent a connection. There is no meaningful relationship between canine CBD and weight-loss medication: nothing here treats, affects or interacts with semaglutide or tirzepatide, and we would be inventing a link if we claimed otherwise. So we have reviewed it as what it is — a pet product — and applied the same tests we would apply anywhere: what is in it, does the dose match the evidence, what do the terms say, and who benefits from the recommendation. The one honest adjacency, offered lightly: dog ownership is associated with higher levels of everyday walking, and walking is among the most sustainable forms of activity for someone protecting lean mass during weight loss — roughly 45% of the weight lost in the STEP 1 body-composition analysis was lean tissue, and movement plus adequate protein is the countermeasure. If your dog gets you out of the house twice a day, that is doing more for your treatment than any supplement we have reviewed this month. Keeping an older dog comfortable enough to keep walking is therefore not entirely beside the point. But that is an argument for seeing your vet about your dog's joints, not for buying a dropper on our recommendation.
Who should buy it and who should not?
Buy it if you want a pet CBD product from a brand that has made the right formulation choices — no xylitol, no THC, human-grade ingredients, a linked certificate, weight-based dosing — and you are treating it as a general wellness purchase rather than a treatment. On those terms it is one of the more carefully assembled products in a category with very little oversight, the subscription terms are honestly disclosed, and the quantified shelter-meal donations are a genuine nicety. Use the free trial if you want, but diarise the renewal. Do not buy it as a substitute for veterinary care for an arthritic or painful dog. The evidence that does exist used roughly ten times the dose on this label, elevated liver enzymes have been reported in canine CBD research, and pain in an older dog deserves a diagnosis — there are licensed veterinary medicines for canine osteoarthritis with far stronger evidence than any CBD product. Talk to your vet first; if they are content, this is a reasonable brand to choose. Do not read "endorsed by iHeartDogs" as independent, and do not pay attention to the struck-through "values". Our disclosure: this programme pays 25%, among the highest in our queue — about $7.50 on a $29.99 bottle — and our central finding is that the dose on the label is a fraction of the dose in the research.
Ask Your Vet About The Dose.
No xylitol, no THC, a linked certificate and dosing by body weight — the right choices. But the label dose is roughly a tenth of the dose in the published canine trials, and a painful dog needs a diagnosis.
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Read Review →Veterinary Disclaimer: This page is informational and is not veterinary or medical advice. Cannanine products are animal supplements, not medicines; no CBD product is approved by the FDA for use in animals, and there is no officially established dose for dogs or cats. Do not use any supplement in place of veterinary diagnosis and treatment. Lameness, stiffness, reluctance to move, or behavioural change in a dog can indicate osteoarthritis, injury, neurological disease, or other conditions requiring examination; licensed veterinary medicines exist for canine osteoarthritis with stronger evidence than any CBD product. Consult your veterinarian before giving CBD to any animal, particularly one that is pregnant or lactating, very young, has liver or kidney disease, has a seizure disorder, or is taking other medication — CBD can interact with drugs metabolised by cytochrome P450 enzymes, which includes many veterinary medicines. Increases in the liver enzyme alkaline phosphatase have been reported in canine CBD research; your veterinarian can advise whether monitoring is appropriate. THC is considerably more toxic to dogs than to humans and cannabis toxicosis is a veterinary emergency: signs include incoordination, disorientation, urinary incontinence, low body temperature, tremors and, rarely, collapse — seek immediate veterinary attention if suspected. Xylitol is highly toxic to dogs and can cause severe hypoglycaemia and liver failure; always read the physical label of any product you give an animal rather than relying on a website. Keep all supplements out of reach of pets and children, since overconsumption of a palatable chew is a common cause of poisoning. Dosing figures on this page are our own arithmetic on published product information, are provided to illustrate a comparison with research protocols, and must not be used to dose an animal — that is a decision for your veterinarian. Nothing on this page relates to the treatment of humans with GLP-1 medication.
Date reviewed: 8 August 2026. The catalogue was retrieved from cannanine.com's public WooCommerce store API on that date and may change; 60 products were listed. Prices observed: Cannanine Ultra-Premium Broad Spectrum CBD Hemp Oil For Dogs And Cats (250mg) $29.99; Hemp Oil for Dogs Organic Broad Spectrum PCR Oil (250mg) $44.99; Ultra-Premium Broad Spectrum Hemp CBD Oil For Dogs (500mg) $49.99 and (1,000mg) $69.99, with 250mg, 500mg and 1,000mg variants also listed at $29.99 across other SKUs; Bacon Flavored CBD Soft Chews for Dogs 60 count $24.99 to $39.99; CBD Mushroom Chews with Turkey Tail 60ct $34.99; multi-buy bundles to $107.97; alongside non-CBD lines including iHeartDogs Pupkin probiotics $24.99, a 24-in-1 multivitamin $34.99, Honey Guard allergy products $12.99 to $79.99 and dental products. Quoted product copy is the brand's own: 'Our product contains no THC'; 'Provides 7 healthy meals to shelter pets in need'; 'Hemp oil is Legal in all 50 states'; 'Features patented Nano-Sized Microemulsion for maximum bioavailability and absorbability (4x smaller particles compared to Liposomal emulsion)'; 'Manufactured in the USA from organically grown Colorado hemp'; 'Tested and found to be free of heavy metals, harmful bacteria, yeast, mold, and other toxins'; 'Made from Human Grade ingredients'; 'The only hemp oil endorsed by iHeartDogs.com'; 'View the Certificate of Analysis (COA) here'; a dosing chart reading '0-5 lbs Standard Dose – 1/8 droppers (.125 ML) Stronger Dose – 1/4 droppers (.25 ML) 6-11 lbs Standard Dose – 1/4...'; anchor pricing of the form 'One bottle: $29.99 ($49.99 value)' and '$44.99 ($65 value)'; 'With every purchase, 3 meals are donated to hungry shelter dogs'; and the free-trial terms 'Customers signing up will receive a free 60-count jar, and we'll send it for just the cost of shipping and tax. (Domestic orders only). This free trial includes a subscription that autoships Cannanine CBD Soft Chews 60-count jar in the time frame the customer selects (Anywhere from 2-8 weeks) after the initial free order is placed, then every 2-8 weeks (based on selected timeframe) thereafter at 15% off MSRP ($39.99) + shipping & tax. Cancel the subscription any time – it's really that simple! Should the subscription remain active and recurring orders process but you do not wish to keep your subscription active, unopened product can be returned for a refund within 90 days and your subscription can be cancelled.' We searched the full retrieved product text, approximately 79,000 characters, for xylitol, grape, raisin, garlic, onion, macadamia, chocolate, theobromine and birch sugar, and found no occurrences; absence from marketing copy is not equivalent to inspection of a physical label, and we did not open or verify the linked certificate of analysis. We note that URLs supplied in the affiliate brief contain the string 'organic-full-spectrum-cbd-oil' while all products in the retrieved catalogue are named 'Broad Spectrum'; we take these to be legacy addresses. Dosing comparison: the 250mg product is stated as a 30ml bottle, giving 8.33mg/ml; a 0.25ml standard dose therefore delivers approximately 2.08mg, or approximately 0.42mg/kg/day for an 11 lb (5.0kg) dog, and approximately 0.84mg/kg/day at double that volume. The comparison protocol is Gamble et al., a double-blind placebo-controlled trial conducted at Cornell University College of Veterinary Medicine and published in Frontiers in Veterinary Science in 2018 (DOI 10.3389/fvets.2018.00165), which administered 2mg/kg of CBD orally twice daily — 4mg/kg/day — and assessed outcomes using the Canine Brief Pain Inventory and the Hudson Visual Analog Scale. We did not read the full paper and make no claim about its effect sizes; increases in alkaline phosphatase have been reported in canine CBD research generally and we cite this as a monitoring consideration rather than a finding of any single study. Dosing in veterinary CBD is not standardised. No CBD product is FDA-approved for animals. The STEP 1 body-composition finding on lean mass is as published. Katalys offer #189 lists 25.00% default commission.
Affiliate Disclosure: This site may receive compensation from affiliate partners. This programme pays 25% of order value, among the highest rates in our affiliate queue. This does not influence our editorial content or review ratings.