GLP-1 Guide

Please note: This review reflects information we gathered on the date it was researched and may now be out of date. Providers frequently change their pricing, plans, medications, and policies. Any ratings, reviews, and customer feedback are gathered from publicly available online sources and may have since changed or no longer be accurate. Always do your own research and confirm the latest details directly with the provider before making any decision.

Vena CBD Review

Half the range is now intoxicating THC, sold as a way to skip the wine glass — pitched at precisely the readers whose medication has already made them want it less.

Vena CBD

CBD & Hemp THC
3.2 / 5

Not a weight-loss product: nothing here treats any condition or aids weight loss, and THC is best known for increasing appetite. If you came to compare treatment, our provider rankings are the page you want.

Vena is a hemp brand in Medterra's portfolio, co-founded in 2019. Checked on 7 August 2026 it listed 24 products from $29.95 to $179.89 — and 12 of them, exactly half, are intoxicating Delta-9 THC. The homepage leads with 'Wine Down, Reimagined' and 'Skip the wine glass', positioning THC seltzers and gummies squarely as an alcohol substitute.

That pitch lands awkwardly for this audience. A randomised trial published in The Lancet on 2 May 2026 found semaglutide reduced monthly alcohol consumption, drinks per drinking day and craving against placebo. Many readers here are already drinking less without effort. Buying an intoxicant to replace one you have stopped wanting is not obviously progress — and THC raises appetite, which cuts against the medication.

Two verification failures matter. The lab-results page promises 'detailed third-party lab reports' but we could not open a single certificate from it, and no laboratory is named. And the 10mg THC gummy page carries no drug-test warning — these will show on a standard screen, and better sellers say so on every page.

Affiliate disclosure: GLP1Drugs.org earns a commission if you buy through the links on this page — 40% on this programme, one of the higher rates we are offered. We have rated it 3.2, could not verify its lab testing, and suggested most readers do not need what it is selling. Verified 7 August 2026.

Visit Vena CBD
Editor's PickRecommended Partner

Our Top Recommended Provider: CoreAge Rx

After reviewing dozens of GLP-1 telehealth providers, CoreAge Rx is the one we recommend most. CoreAge Rx is one of our partners — read on for why we recommend them:

  • Flat-Rate Pricing

    Same cost at every dose level — no price jumps as you titrate up.

  • Verified Pharmacies

    US-licensed physicians and NABP-verified 503A compounding pharmacies you can trust.

  • Everything Included

    Medication, supplies, free shipping, and ongoing clinical support — no hidden fees.

💬

Active Community of Members

Ask questions, share progress, and get answers from other patients on the same journey — alongside ongoing clinical support from your care team.

Visit CoreAge Rx →

0

Lab Certificates We Could Open

12/24

Products That Are Intoxicating

$8.88

Per 10mg THC Gummy

4.0

Trustpilot, 100 Reviews

The Alcohol Swap

This brand is selling a substitute for drinking. Here is what the evidence says about that, for readers on a GLP-1.

GLP-1s Already Reduce Drinking

A Lancet trial published on 2 May 2026 found semaglutide cut monthly alcohol consumption, drinks per drinking day and craving against placebo over 26 weeks in people with alcohol use disorder and obesity

You May Not Need A Substitute

If the medication has already blunted the urge, buying a $79.95 jar of THC gummies to replace a habit you have stopped wanting is solving a problem you no longer have

It Is Still An Intoxicant

Swapping wine for 10mg THC is a substitution, not abstinence. 'Hangover-free' describes one specific consequence of alcohol, not the absence of all consequences

THC Increases Appetite

The best-documented effect of THC on eating works directly against what a GLP-1 does. That is a real tension in using one alongside the other

Both Act On The Gut

GLP-1s slow gastric emptying and cause nausea; heavy chronic cannabis use is associated with cyclic vomiting. If you develop persistent vomiting on both, that needs a clinician, not a dose adjustment you guess at

No GLP-1 Is Approved For This

Every use of a GLP-1 for drinking is off-label and the evidence, while genuinely promising, is young. Do not start or stop anything on the strength of it

None of this is a reason to be alarmed if you enjoy a THC seltzer occasionally. It is a reason to notice what is being sold to you and when. If you are cutting down on alcohol because your medication made it easy, that is a good outcome on its own — it does not require a purchase to complete it. And if you are drinking in a way that worries you, that is a conversation with a clinician rather than a product decision.

What We Could And Could Not Verify

Checked against the brand's own pages on 7 August 2026.

ItemWhat we foundStatus
30-day refund“Refund for the full purchase price within 30 days of the date the product was delivered”Verified
Does it cover THC?Wording says “our CBD products”; the THC half is not addressedUnclear
Certificates of analysisDedicated page promises them; no certificate could be opened, no lab namedNot verifiable
Drug-test warningNone on the 10mg THC gummy pageAbsent
Return shipping“Customers are responsible for covering all costs on return shipping”You pay
12 Nov 2026 exposure90mg THC per gummy jar against an incoming 0.4mg per-container cap~225× over

Pros & Cons

Pros

  • A clear 30-day refund: 'If you are for any reason unsatisfied with our CBD products, you may request a refund for the full purchase price within 30 days of the date the product was delivered'
  • Trustpilot rates it 4.0 out of 5 across 100 reviews — a fair score on a reasonable sample for this category
  • Doses are stated plainly on the product page: 10mg THC, 10mg CBD and 2mg CBG per xtra bliss gummy
  • Products are labelled 21+, and the required FDA disclaimer appears in the footer
  • Part of Medterra's brand portfolio rather than a standalone operation with no corporate substance
  • A low-dose entry point exists: the 2mg THC seltzers at $29.95 are a genuinely cautious starting dose
  • Free shipping over $75, and a published help centre with stated support hours

Cons

  • We could not retrieve a single certificate of analysis from the dedicated lab-results page, and no testing laboratory is named anywhere
  • No drug-test warning appears on the 10mg THC gummy page — these will show up on a standard screen, and better hemp sellers say so
  • The refund wording covers 'our CBD products'; whether it extends to the THC half of the catalogue is not stated
  • Customers pay return shipping, and damage claims need photo proof inside 72 hours
  • At $79.95 for 9 gummies, xtra bliss works out at roughly $8.88 per 10mg dose
  • Seltzers are explicitly excluded from the free-shipping threshold, and they are the fastest-growing part of the range
  • Twelve of the 24 live products are intoxicating THC, all of it exposed to the 12 November 2026 federal hemp redefinition
  • The site never mentions Medterra, and Medterra is subject to a non-binding letter of intent to merge with Splash Beverage Group
  • The marketing targets the alcohol-replacement moment, which is exactly when a GLP-1 patient is least in need of another intoxicant

How It Compares

Against the other hemp brands we have reviewed, on the two things that separate them.

BrandRatingBatch certificatesDrug-test disclosure
Vena CBD3.2None we could open; no lab namedAbsent on the 10mg gummy
Cheech & Chong3.4Batch PDFs we downloaded ourselvesStated plainly on product pages
CleanAF CBD3.5Batch-linked reportsIn-house Florida manufacturing
Joy Organics4.0Published COAs, USDA organic90-day refund, BBB A+

Our Verdict

3.2 / 5 — a competent brand with a fair refund policy and a decent review record, selling intoxicants it will not show you the lab reports for, to people whose medication has already reduced their appetite for them.

The good parts are real. A 30-day, any-reason, full-purchase-price refund is above average. Trustpilot at 4.0 across 100 reviews is a respectable score. Doses are stated clearly on the product page, products are marked 21+, the FDA disclaimer is present, and there is a genuinely cautious 2mg entry point in the seltzer range for anyone who wants to try a low dose. Sitting inside Medterra's portfolio gives it more corporate substance than a one-person storefront.

But we judge hemp brands mainly on whether they will prove what is in the jar, and this one would not. A page that promises 'detailed third-party lab reports' and then yields no certificate and names no laboratory is the weakest showing on that measure of any hemp brand we have reviewed — and it is a low bar, since competitors let you select a batch number and download the signed PDF. Add the missing drug-test warning on a 10mg THC product, a refund policy whose wording only mentions CBD, roughly $8.88 a gummy, and a catalogue half of which is 225 times over the THC limit arriving on 12 November 2026, and the case thins considerably. If you want the CBD line, ask for your batch certificate before you open it. If you are drinking less because of your medication, take the win rather than buying a substitute.

Visit Vena CBD

Frequently Asked Questions

Does it make sense to swap wine for THC on a GLP-1?

This is the question the brand's own marketing raises, and it deserves a straight answer. Vena leads with 'Wine Down, Reimagined' and 'Skip the wine glass', positioning THC seltzers and gummies as an alcohol substitute. Meanwhile the evidence that GLP-1 medications reduce drinking has become genuinely strong: a randomised trial in JAMA Psychiatry in 2025 found low-dose semaglutide reduced laboratory alcohol consumption, drinks per drinking day and weekly craving in adults with alcohol use disorder, and a larger randomised, double-blind, placebo-controlled trial published in The Lancet on 2 May 2026 found semaglutide produced larger decreases in total monthly consumption, drinks per drinking day and self-reported craving over 26 weeks in people with alcohol use disorder and comorbid obesity. So many readers will already be drinking less without trying. Two things follow. First, you may simply not need a replacement — spending $79.95 on gummies to substitute for something you have stopped wanting is not a saving. Second, and more importantly, swapping alcohol for THC is not the same as reducing intoxicant use; it is changing which intoxicant. If you are drinking less because of your medication, the useful move is usually to let that happen rather than to fill the gap. And note: no GLP-1 is approved to treat alcohol use disorder, and all such use is off-label.

Are there actual lab results?

We could not get to one, which is the main reason this scores where it does. Vena has a dedicated lab-results page that reads well — it says every product is 'third-party tested twice', once on the hemp distillate before production and again on the finished product, and promises 'detailed third-party lab reports'. What we could not do, on 7 August 2026, was open an actual certificate from it. The page carries no PDF links and no visible certificate links, and no testing laboratory is named anywhere on it. In fairness, the page does contain embedded elements and selector controls we could not resolve, so it is possible certificates are served through a mechanism our tools did not reach — we are reporting that we could not verify them, not asserting that none exist. Either way, compare this with brands in the same category that let you pick your batch number and download the signed PDF. If you buy, ask customer service for the certificate matching the lot on your jar before you take it.

Will these show up on a drug test?

Almost certainly, and the product page does not tell you. The xtra bliss gummies contain 10mg of real Delta-9 THC each, and the seltzers 2mg or 10mg per can. Hemp-derived Delta-9 is chemically the same molecule that urine screens detect; being federally compliant on a dry-weight basis has nothing to do with whether you test positive. We checked the xtra bliss product page specifically and found no drug-test warning on it. That is a meaningful omission — other hemp sellers we have reviewed state plainly on every product page that their products will show up on a standard drug test. If you are subject to workplace, custody, probation or athletic testing, do not buy anything from the THC half of this catalogue.

What does it cost?

Checked on 7 August 2026 the live catalogue held 24 products from $29.95 to $179.89, with a median of $69.95. The headline items: xtra bliss THC gummies at $79.95 for 9 gummies, which is about $8.88 per 10mg dose; Lights Out sleep THC gummies at $69.95; Full Spectrum Restful Night Bites at $49.95; Happy Tonix seltzers at $29.95 for the 2mg cans and $39.95 for the 10mg. Bundles run to $175.88. Free shipping starts at $75 — but the site notes 'Seltzers do not qualify for free shipping', which is worth knowing given seltzers are the cheapest way in. At roughly nine dollars a gummy this sits at the premium end, and the premium is not explained by anything we could verify about the testing.

Who actually owns Vena?

Medterra, and the site does not say so. Vena is a brand within Medterra's portfolio — it was co-founded in 2019 by Tamra Judge and sits alongside Medterra's other brands. The affiliate programme itself lists the advertiser as Medterra CBD LLC, but we found no mention of Medterra anywhere on venacbd.com. There is a further wrinkle worth knowing if you are considering a subscription or relying on the 30-day guarantee: Splash Beverage Group has disclosed a non-binding letter of intent for a proposed merger with Medterra CBD, LLC. A letter of intent is not a completed deal and may never close, so this is context rather than a prediction. But brands change hands, and guarantees are honoured by whoever owns the entity at the time.

What happens to these products in November 2026?

Most of them stop being federally lawful, which is the single biggest thing to factor into any subscription decision. On 12 November 2025 the President signed H.R. 5371, which redefines hemp with effect from 12 November 2026: total THC of no more than 0.3% on a dry weight basis, now explicitly inclusive of THCA and delta-8, and a cap of 0.4mg of total THC per container for a consumable. A jar of xtra bliss holds 9 gummies at 10mg each, so 90mg per container — about 225 times that limit. Even the cautious 2mg seltzer is five times it. The U.S. Hemp Roundtable has estimated the new standard renders roughly 95% of existing hemp cannabinoid products federally unlawful. Twelve of Vena's 24 live products are THC. The non-intoxicating CBD tinctures, capsules and skincare are the part of this range most likely to survive; the part the brand is currently marketing hardest is not.

Is the CBD side worth buying?

It is the more defensible half, with the same caveat that applies to the whole category. Vena's non-intoxicating line — tinctures, gel capsules, Restful Night bites, the soaking salts and the skincare — carries none of the intoxication, drug-test or November exposure of the THC range, and the 30-day refund explicitly covers 'our CBD products'. What we cannot tell you is whether it is well made, because we could not retrieve a certificate of analysis to check potency or contaminants. The only FDA-approved cannabidiol medicine remains Epidiolex, for three specific seizure disorders; everything else is sold as a supplement in a regulatory grey area, and the evidence for sleep and stress benefits is thinner than the marketing across this whole industry implies. If you want CBD, brands that let you download your batch certificate are the better buy.

Who should not use these?

Anyone under 21. Anyone pregnant, trying to conceive or breastfeeding. Anyone with a personal or family history of psychosis, schizophrenia or bipolar disorder, since THC can precipitate psychiatric symptoms. Anyone with significant cardiovascular disease, given THC's effect on heart rate. Anyone driving, operating machinery or on call within several hours of a dose. Anyone subject to drug testing. Anyone taking sedatives, benzodiazepines, opioids or alcohol, because the effects compound — and 'hangover-free' does not mean interaction-free. For CBD specifically, it inhibits cytochrome P450 enzymes and can raise levels of other medicines, so check with a pharmacist if you take anticoagulants, anti-epileptics or anything with a narrow therapeutic index. If you take a GLP-1, tell your prescriber: the two have opposing effects on appetite and both act on the gut. This page is information, not medical advice.

Ask For The Batch Certificate

The refund window is fair and the doses are clearly labelled. Before you open anything, ask customer service for the lab report matching the lot number on your jar.

Visit Vena CBD

Medical Disclaimer: This page is informational and is not medical advice. These are hemp products for adults 21 and over, not treatments for any condition and not weight-management aids. THC is intoxicating, impairs coordination and judgement, may trigger anxiety or psychotic symptoms in susceptible people, will show up on a standard drug test, and interacts with alcohol, sedatives and some prescription medicines. Do not use in pregnancy, while trying to conceive, or while breastfeeding, and do not drive or operate machinery after a dose. CBD inhibits cytochrome P450 enzymes and can raise levels of other medications. No GLP-1 receptor agonist is approved to treat alcohol use disorder; the trial evidence described here concerns off-label use and should not prompt anyone to start, stop or alter treatment without their clinician. Anyone concerned about their drinking should speak to a healthcare professional.

Date reviewed: 7 August 2026. The 24-product catalogue, prices, dosing, the 30-day refund wording, the return-shipping term and the free-shipping seltzer exclusion were taken from Vena's own site and product data on that date and may change. We attempted to retrieve a certificate of analysis from the brand's lab-results page and could not; the page contains embedded elements we were unable to resolve, so we report a failure to verify rather than an absence of testing. No testing laboratory is named on that page. No drug-test warning was present on the xtra bliss product page when checked. Trustpilot's 4.0 across 100 reviews was read from that profile's structured data. Vena is described in public sources as a brand within Medterra's portfolio, co-founded in 2019; Splash Beverage Group has publicly disclosed a non-binding letter of intent for a proposed merger with Medterra CBD, LLC, which may not complete. The alcohol findings cited are a 2025 randomised trial in JAMA Psychiatry and a randomised, double-blind, placebo-controlled trial published in The Lancet on 2 May 2026; both concern off-label use in specific populations. The federal hemp redefinition was enacted in H.R. 5371, signed 12 November 2025, effective 12 November 2026.

Affiliate Disclosure: This site may receive compensation from affiliate partners. This does not influence our editorial content or review ratings.